Friday, January 31, 2020

RNA-Seq and Microarray Analysis Research Paper Example | Topics and Well Written Essays - 2500 words

RNA-Seq and Microarray Analysis - Research Paper Example Therefore, dogs become the best models for indentifying the genetic underpinnings that are associated with cancer in humans (Mooney, et al., 2013). The fact that dogs and humans depict similarities in cancer treatment and responses also allow for the opportunity to apply advanced cancer diagnostic tools. This is meant to enhance the understanding of the possible treatment of cancerous diseases for the benefit of both dogs and man (Mooney, et al., 2013). The typified canine lymphoma in dogs presents some analogous characteristics with the human Non-Hodgkin’s Lymphoma (NHL) in form of biological and other clinical features. This makes it possible to understand this type of cancer in humans (Mooney, et al., 2013). The canine lymphoma is the most common canine cancerous disease in dogs accounting for 24% occurrence. On the other hand, the NHL is the most common cancer in the USA, while it has almost doubled throughout the world in the last 35 years (Mooney, et al., 2013). Canine cancer is a multi-centric lymphadenopathy cancer that has no other organs involvement, requiring the same type of treatment that apply the multi-agent protocol, which is the standard of care for the NHL cancer in humans (Mooney, et al., 2013). Therefore, the understanding of the canine lymphoma is acceptable for enabling the understanding of the diagnostic process and therapeutic treatment of the NHL patients (Mooney, et al., 2013). The methodology applied in this study first sought to attain the consent of the dog owners that were participating in the study. This was followed by seeking for the approval of the Institutional Animal Care and Use Committee since it the body responsible ensuring the welfare of animals subjected under studies. The sample applied in the study was 30 dogs, from which Fine needle aspirates (FNAs) were collected for analysis (Mooney, et al., 2013). The dogs qualifying for the study required to have a lymph

Thursday, January 23, 2020

Hemingway and Fitzgerald Essay -- Friendships Writers Authors Essays

Hemingway and Fitzgerald Ernest Hemingway and F. Scott Fitzgerald, the parties of one of the most famously infamous relationships in literary history met for the first time in late April 1925 at The Dingo Bar, a Paris hangout for the bohemian set. In his novel A Moveable Feast (published posthumously) Hemingway describes his first impressions of Fitzgerald: â€Å"The first time I ever met Scott Fitzgerald a very strange thing happened. Many strange things happened with Scott, but this one I was never able to forget. He had come into the Dingo bar in the rue Delambre where I was sitting with some completely worthless characters, had introduced himself and introduced a tall, pleasant man who was with him as Dunc Chaplin, the famous pitcher†¦I much preferred him to Scott†¦Scott was a man then who looked like a boy with a face between handsome and pretty†¦The mouth worried you until you knew him, and then it worried you more.†(Hemingway, 149) The above passage, as several scholars have pointed out, is an excellent example of Hemingway’s â€Å"selective memory† as far as his descriptions of Scott are concerned, and in a larger part, is also indicative of the rather mythological quality their relationship took on over the years.(Bruccoli, 1) In his book Fitzgerald and Hemingway: A Dangerous Friendship, famed Fitzgerald academic Matthew J. Bruccoli writes that in fact, â€Å"Chaplin was not in Paris in 1925; Chaplin was not in Europe in 1925; Chaplin never met Hemingway.†(1) He goes on to raise the point that has somewhat frustrated scholars and students of the duo for the past half a century: that much of what is â€Å"known† about their relationship is through their correspondence and Hemingway’s writing, both of which are ... ...ngway vs. Fitzgerald: The Rise and Fall of a Literary Friendship. Woodstock, New York: Overlook, 1999. Hemingway, Ernest. A Moveable Feast. New York: Simon and Schuster, 1964. â€Å"Fitzgerald, Hemingway, and The Sun Also Rises† This website gives a thorough description of the story behind the publication of SAR as well as links to other helpful Hemingway sites, and a well-written article by scholar Paige Grande. â€Å"Scott and Ernest: A Logical Friendship† This is a great website that has a lot of detailed information about Hemingway’s literary and personal life. Scholar Kelly Dupuis does an excellent job of sifting through the sometimes dense research done by Bruccoli and others, which makes the site clear and accessible. Hemingway and Fitzgerald Essay -- Friendships Writers Authors Essays Hemingway and Fitzgerald Ernest Hemingway and F. Scott Fitzgerald, the parties of one of the most famously infamous relationships in literary history met for the first time in late April 1925 at The Dingo Bar, a Paris hangout for the bohemian set. In his novel A Moveable Feast (published posthumously) Hemingway describes his first impressions of Fitzgerald: â€Å"The first time I ever met Scott Fitzgerald a very strange thing happened. Many strange things happened with Scott, but this one I was never able to forget. He had come into the Dingo bar in the rue Delambre where I was sitting with some completely worthless characters, had introduced himself and introduced a tall, pleasant man who was with him as Dunc Chaplin, the famous pitcher†¦I much preferred him to Scott†¦Scott was a man then who looked like a boy with a face between handsome and pretty†¦The mouth worried you until you knew him, and then it worried you more.†(Hemingway, 149) The above passage, as several scholars have pointed out, is an excellent example of Hemingway’s â€Å"selective memory† as far as his descriptions of Scott are concerned, and in a larger part, is also indicative of the rather mythological quality their relationship took on over the years.(Bruccoli, 1) In his book Fitzgerald and Hemingway: A Dangerous Friendship, famed Fitzgerald academic Matthew J. Bruccoli writes that in fact, â€Å"Chaplin was not in Paris in 1925; Chaplin was not in Europe in 1925; Chaplin never met Hemingway.†(1) He goes on to raise the point that has somewhat frustrated scholars and students of the duo for the past half a century: that much of what is â€Å"known† about their relationship is through their correspondence and Hemingway’s writing, both of which are ... ...ngway vs. Fitzgerald: The Rise and Fall of a Literary Friendship. Woodstock, New York: Overlook, 1999. Hemingway, Ernest. A Moveable Feast. New York: Simon and Schuster, 1964. â€Å"Fitzgerald, Hemingway, and The Sun Also Rises† This website gives a thorough description of the story behind the publication of SAR as well as links to other helpful Hemingway sites, and a well-written article by scholar Paige Grande. â€Å"Scott and Ernest: A Logical Friendship† This is a great website that has a lot of detailed information about Hemingway’s literary and personal life. Scholar Kelly Dupuis does an excellent job of sifting through the sometimes dense research done by Bruccoli and others, which makes the site clear and accessible.

Wednesday, January 15, 2020

Racism and Prejudice in To Kill a Mockingbird Essay

In Harper Lee’s To Kill a Mockingbird, an African American, named Tom Robinson, is accused of raping a white girl. Throughout the story we learn that Maycomb County, Alabama is full of people who are considered to be racist. From the beginning, even before Robinson’s trial began, everyone believed that he would be found guilty. At the end of Robinson’s trial he is found guilty. Another issue throughout the novel is many of the citizens of Maycomb are prejudice against others in the town, such as Boo Radley. A statement one may conclude after reading To Kill a Mockingbird is that racism and prejudice are comparable to habits. Racism, prejudice, and habits may be acquired by watching and listening one’s family, as well as others one interacts with, from a young age. Both racism and prejudice, like most habits, can be broken with some effort and a set mind, but one must first understand what it is they are doing wrong. To understand what is wrong with one’s behavior one might seek an adult or someone they respect to explain what it is that is wrong and why it may be considered wrong. In Harper Lee’s, To Kill a Mockingbird, the character development throughout the story shows that racism and prejudice are acquired through one’s interaction with others and that it is possible to break these mindsets. Throughout the majority of this book Scout is afraid of Boo Radley, but towards the end, after Boo Radley carries Scout’s brother home, she realizes he is not such a bad person after all (270). Scout is only afraid of Boo Radley because of the rumors she heard about him from others that she interacted with. Once Scout actually met Boo Radley herself she realized he is not scary, he just keeps to himself. The fact that Scout has an opinion about Boo Radley before actually meeting him shows that she is influenced by others around her. One may not consider this a favorable characteristic, but it is relatable to everyday life. The majority of people are easily influenced or know someone who is easily influenced, so one may comprehend more easily why racism and prejudice exist. A similar situation to the last one takes place in the beginning of the book. Most of the people in the book know very little about Boo Radley, but â€Å"[a]ccording to Miss Stephanie†¦As Mr. Radley passed by, Boo drove the  scissors into his parent’s leg, pulled them out, wiped them on his pants, and resumed his activities† (11). Miss Stephanie tells the children and others this which causes the children and the others to form a prejudicial view about Boo Radley without ever having met him. The fact that Miss Stephanie’s statement affected others’ opinions about Boo shows how one’s statement can affect the logical reasoning of others. The others had no way of knowing if Miss. Stephanie’s statement was true or not, yet they still believed her. One may come to the conclusion that others believe something one says just to feel accepted or included.

Tuesday, January 7, 2020

Essay on Euthanasia and Doctor-Assisted Suicide - 1175 Words

Understanding Euthanasia and Assisted Suicide This paper will address some of the more popular points of interest involved with the euthanasia-assisted suicide discussion. There are less than a dozen questions which would come to mind in the case of the average individual who has a mild interest in this debate, and the following essay presents information which would satisfy that individuals curiosity on these points of common interest. Euthanasia and assisted suicide are legal in the state of Oregon and in the country of the Netherlands; these are the only two jurisdictions in the world where laws specifically permit euthanasia or assisted suicide. Oregon permits assisted suicide.(Oregon) The Netherlands permits both†¦show more content†¦It would also be assisted suicide if a patient pushes a switch to trigger a fatal injection after the doctor has inserted an intravenous needle into the patients vein. Its true that modern technology keeps people alive who previously would have died earlier. A century ago, high blood pressure, pneumonia, appendicitis, and diabetes likely meant death, often accompanied by excruciating pain. Women had shorter life expectancies than men since many died in childbirth. Antibiotics, immunizations, modern surgery and many of todays routine therapies or medications were unknown then. A lot of people think that euthanasia or assisted suicide is needed so patients wont be forced to remain alive by being hooked up to machines. But the law already permits patients or their surrogates to withhold or withdraw unwanted medical treatment even if that increases the likelihood that the patient will die. Thus, no one needs to be hooked up to machines against their will. Neither the law nor medical ethics requires that everything be done to keep a person alive. Insistence, against the patients wishes, that death be postponed by every means available is contrary to law and practice. There comes a time when continued attempts to cure are not compassionate, wise, or medically sound. T hats when hospice, including in-home hospice care, can be of great help. 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Constantly was I running into problems, and this ended up taking me much longer than I had originally planned. Writing about the opposing side of this topic was very hard, as I usually caught myself writing things that I couldn’t make work in my paper. The writing was very tough to keep on track because it isn’t actually how I feel. This essay helped me to better understand the argument that is presented from